Endocrine Abstracts

Thirty-two years old female G2P1A0 seen at our endocrinology clinic 9 years ago complaining of persistent menstrual irregularities associated to elevated prolactin values. MRI done revealed a pituitary microadenoma. However, she refused treatment for microprolactinoma. Four years afterwards, patient return complaining of recurrent episodes of headache. Repeated MRI showed a pituitary macroadenoma, so start on cabergoline treatment.Once more, patient was ...

Background: Acromegaly most commonly results from an excess production of GH and secondary increase in IGF1. More than 95% of the time from the pituitary gland, but the source of excess GH secretion may not necessarily be pituitary in origin. Ectopic acromegaly may arise due to neuroendocrine tumors by production of GHRH and in <0.5% of the cases from ectopic pituitary remnants in the sphenoid sinus.Clinical case: We present a case of a 37 years old ...

Introduction: Isolated ACTH deficiency (IAD) is a rare entity characterized by secondary adrenal insufficiency with low levels of serum cortisol, decreased production of ACTH, adequate secretion of other pituitary hormones and normal pituitary structure on radioimaging. Due to the rarity of its occurrence the prevalence of IAD as a cause of secondary adrenal insufficiency has not been determined. To our knowledge 200 cases are described in the literature. Impairment of GH secr...